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Individual response varies considerably, with some participants experiencing meaningful fat loss while others showed minimal changes

Subsequently, STAT3 undergoes phosphorylation (p-STAT3), which is in turn translocated to the nucleus, where it modulates the transcription of downstream target genes that participate in numerous cellular processes, such as inflamation, proliferation, EMT, invasion, and metastasis (Fig

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Excess ionic iron leads to iron accumulation, subsequently resulting in an iron-dependent mode of cell death known as ferroptosis [18, 19]